The HGH peptide market is an ever changing world. Peptides such as Sermorelin, GHRP-2, GHRP-6, and others have been incredibly popular in the past. Things have changed though. Now we have some players to the game that are revolutionizing the entire philosophy around managing patients who are interested in optimizing their overall health without compromising it at the same time with unwanted side effects.
First of all, let’s examine what a peptide (in the HGH) sense actually us. It is a synthetic protein structure that mimics our bodies precursor hormones to HGH. There are several hormonal mechanisms that activate the pituitary to make HGH. Two of the primary ones are Growth Hormone Releasing Hormone (GHRH) and Ghrelin. Ghrelin is a hunger hormone that stimulates a person to eat. This fires off HGH production to maximize protein synthesis and other metabolic operations to take full advantage of the processing of the food taken in. GHRH is a different hormone that also stimulates the pituitary to produce HGH.
Our preferred peptides are analogs of these two hormones. Ibutamoren (Mk-677) is a ghrelin mimic. It is a hunger hormone, therefore it will usually cause the patient to eat more. This can be a good thing or a bad thing depending on the goals of the individual. One huge plus with Ibutamoren is that is orally available. It can be dosed up to 50mg daily and the patients IGF-1 levels improve tremendously as dosage increases.
Ipamorelin is a GHRH analog. The benefit of this peptide is that there is no hunger associated with it at all. The main drawback is that it requires daily injections to administer.
Both of these peptides are similar in strength, so deciding between the two is usually determined by the individual’s goals and ability to stay compliant with injections.